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Thyroid Diseases

Symptoms and Complications

Hypothyroidism results in low levels of T4 and T3 in the blood. Not having enough T4 and T3 in the blood causes your metabolism to slow down.

Common symptoms include:

  • coarse and dry hair
  • confusion or forgetfulness (often mistaken for dementia in seniors)
  • constipation
  • depression
  • dry, scaly skin
  • fatigue or a feeling of sluggishness
  • hair loss
  • increased menstrual flow (women)
  • intolerance to cold temperatures
  • irritability
  • muscle cramps
  • slower heart rate
  • weakness
  • weight gain

If hypothyroidism isn't treated, the symptoms will progress. Rarely, a severe form of hypothyroidism, called myxedema, can develop. Symptoms of myxedema include:

  • low body temperature
  • dulled mental processes
  • congestive heart failure, a condition where the heart cannot pump enough blood to meet the body's needs

Myxedema coma occurs in people with severe hypothyroidism who are exposed to additional physical stresses such as infections, cold temperatures, trauma, or the use of sedatives. Symptoms include the loss of consciousness, seizures, and slowed breathing.

Hyperthyroidism results in high levels of T4 and T3 circulating in the blood. These hormones speed up your metabolism. Some of the most common symptoms include:

  • increased heart rate with abnormal rhythm or pounding (palpitations)
  • high blood pressure
  • increased body temperature (feeling unusually warm)
  • increased sweating
  • clamminess
  • feeling agitated or nervous
  • tremors in the hands
  • feeling of restlessness even though the person is tired or weak
  • increased appetite accompanied by weight loss
  • interrupted sleep
  • frequent bowel movements, sometimes with diarrhea
  • puffiness around the eyes, increased tears, sensitivity to light, or an intense stare
  • bone loss (osteoporosis)
  • stopped menstrual cycles

Graves' disease, in addition to the common symptoms of hyperthyroidism, may cause a bulge in the neck (goiter) at the location of the enlarged thyroid gland. It also causes the eyes to bulge out, which may result in double vision. Sometimes, the skin over the shins becomes raised.

If hyperthyroidism is left untreated or is not treated properly, a life-threatening complication called thyroid storm (extreme overactivity of the thyroid gland) can occur. Symptoms include:

  • confusion
  • coma
  • fever
  • high blood pressure
  • irregular heartbeat, which can be fatal
  • jaundice associated with liver enlargement
  • mood swings
  • muscle loss
  • restlessness
  • shock
  • weakness

Thyroid storm, considered a medical emergency, can also be triggered by trauma, infection, surgery, uncontrolled diabetes, pregnancy or labor, or taking too much thyroid medication.


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